Frequently, the balance among these different substances (and the changes in them) is just as important as the concentrations.Ĭalcium can be used as a diagnostic test if a person has symptoms that suggest: Measuring urine calcium can help determine whether the kidneys are excreting the proper amount of calcium, and testing for vitamin D, phosphorus, and/or magnesium can help determine whether other deficiencies or excesses exist. If the blood calcium is abnormal, measuring calcium and PTH together can help determine whether the parathyroid glands are functioning normally. PTH and vitamin D are responsible for maintaining calcium concentrations in the blood within a narrow range of values. To help diagnose the underlying problem, additional tests are often performed to measure ionized calcium, urine calcium, phosphorus, magnesium, vitamin D, parathyroid hormone (PTH) and PTH-related peptide (PTHrP). When an abnormal total calcium result is obtained, it is viewed as an indicator of an underlying problem. It is included in the comprehensive metabolic panel (CMP) and the basic metabolic panel (BMP), groups of tests that are performed together to diagnose or monitor a variety of conditions. The test may also be ordered if a person has symptoms of a parathyroid disorder, malabsorption, or an overactive thyroid.Ī total calcium level is often measured as part of a routine health screening. Measurement of the amount of calcium in the urine is used to determine how much calcium the kidneys are eliminating.Ī blood calcium test is ordered to screen for, diagnose, and monitor a range of conditions relating to the bones, heart, nerves, kidneys, and teeth.
Some calcium is lost from the body every day, filtered from the blood by the kidneys and excreted into the urine and sweat. The ionized calcium test measures only the free, metabolically active form.
#Ionized calcium istat free
The total calcium test measures both the free and bound forms. There are two tests to measure blood calcium. The remaining half is “bound” to proteins, primarily albumin and to a lesser extend globulins, with a smaller amount complexed to anions, such as phosphate, and these bound and complexed forms are metabolically inactive. Roughly half of the calcium in the blood is “free” and is metabolically active. Calcium levels are tightly controlled if there is too little absorbed or ingested, or if there is excess loss through the kidney or gut, calcium is taken from bone to maintain blood concentrations. This test measures the amount of calcium in the blood or urine, which reflects the amount of total and ionized calcium in the body.Ībout 99% of calcium is found complexed in the bones, while the remaining 1% circulates in the blood. Calcium is needed for blood clotting and is crucial for the formation, density, and maintenance of bones and teeth. It is essential for cell signaling and the proper functioning of muscles, nerves, and the heart.
#Ionized calcium istat portable
pH, calculated HCO3, K and Ca measured by two methods showed significant difference, but observed differences would not affect clinical decisions except ionized calcium.ĬONCLUSIONS: This study shows that blood gas and electrolyte analysis using the I-STAT portable device is comparable with that performed by a conventional Chiron 348 pH/blood gas/ electrolytes analyzer except ionized calcium.Calcium is the most abundant and one of the most important minerals in the body. RESULTS: PO2, PCO2 and Na measured with I-STAT system and Chiron 348 PH/ blood gas/ electrolytes analyzer showed no significant differences. Differences between results of two methods were analyzed by paired t-test (p<0.05). METHODS: Thirty samples from the arterial blood were simultaneously analyzed with I-STAT system and with Chiron 348 pH/blood gas/ electrolytes analyzer. We evaluated the performance of the I-STAT portable clinical analyzer for measuring blood gases (pH, PCO2, PO2) and whole blood electrolytes (sodium, potassium and ionized calcium) with reference to a conventional blood gas analyzer (Chiron 348 pH/ blood gas/electrolytes). 기존의 혈액가스분석기 (Chiron348 ph/blood gas/electrolytes analyzer)와 I - STAT 휴대용 분석기의 비교Ĭomparison of Conventional Chiron 348 pH/blood Gas/electrolytes Analyzer and i-STAT Portable Clinical Analyzerĭong Suk Chung, Jong Bun Kim, Sie Hyun Youĭepartment of Anesthesiology, College of Medicine, The Catholic University of Korea, Seoul, Korea.īACKGROUND: The development of so-called "Point-of-care" (POC) devices for blood or urine analysis has resulted in many systems that are widely used at home or at the bedside. Korean Journal of Critical Care Medicine 2000 15(1): 35-40.
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